Pharmacotherapy for Cardiovascular Disorders Essay Assignment Paper

Posted: November 18th, 2022

Pharmacotherapy for Cardiovascular Disorders Essay Assignment Paper

Assignment for Week 2: Case Study Patient HM has a history of atrial fibrillation and a transient ischemic attack (TIA). Thepatient has been diagnosed with type 2 diabetes, hypertension, hyperlipidemia and ischemic heart disease. Drugs currently prescribed include the following: Warfarin 5 mg daily MWF and 2.5 mg daily T, TH, Sat, Sun Aspirin 81 mg daily Metformin 1000 mg po bid Glyburide 10 mg bid Atenolol 100 mg po daily Motrin 200 mg 1–3 tablets every 6 hours as needed for pain Explain how the factor you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned. Describe how changes in the processes might impact the patient’s recommended drug therapy. Be specific and provide examples. Explain how you might improve the patient’s drug therapy plan and explain why you would make these recommended improvements Pharmacotherapy for Cardiovascular Disorders Essay Assignment Paper.


Patient HM has had an episode of atrial fibrillation in addition to a transient ischemic stroke. The presence of atrial fibrillation raises the likelihood that the client may have a stroke in the future. The client has already had a transient ischemic attack (TIA), and there is a high chance of recurrence. When prescribing medicines and administering treatment, it is important to take the client’s age into consideration. Because of the significant disparity between pharmacokinetics and pharmacodynamics, different responses to the problem of drug therapy have been seen Pharmacotherapy for Cardiovascular Disorders Essay Assignment Paper.

Age as a Factor

There is a strong relationship between a people’s their risk of developing hypertension and age. Increased risk of developing the disease is associated with increasing age. There is a significant chance that a person may develop cardiovascular problems when there is no therapy available or when treatment is pushed back (Choi, et al, 2020). Furthermore, as one’s age increases, their chances of developing atrial fibrillation increase significantly. As a result, age is one of the most significant risk factors associated with ischemic stroke in those who have atrial fibrillation .comorbidities such as diabetes and hyperlipidemia, as well as the client’s age and gender, are all indicators of variables that contribute to the occurrence of ischemia events again and again. If you are working with such individuals, the most important thing to remember is that controlling medicines intended to avoid stroke is your first priority.

How Changes in the Processes Might Impact the Patient’s Recommended Drug Therapy

As a person’s age increases, the pharmacokinetics of a drug will change as well. Both renal clearance and hepatic are reduced as a result of this treatment. Additionally, there is the matter of an increase in the amount of distrusted medicines, which is a growing concern for many. The problem results in a longer rate of elimination as well as an increase in the concentration of medicines in the urine. When dealing with elderly people, it is necessary to reduce the amount of medication used (Arcangelo et al., 2017). Because of the problem of pharmacodynamics, elderly individuals are at a higher risk of developing medication sensitivity. Cardiovascular, Psychotropic and anticoagulants medications are examples of this kind of medication.


How to Improve the Patient’s Drug Therapy Plan

The usage of satin is required for the improvement of the client’s medication treatment. In certain cases, it may be necessary to contemplate prescribing drugs that will reduce the patient’s blood pressure (Korhonen, et al, 2020). This kind of medicine will be required since it will aid in lowering the risk associated with both coronary heart disease and stroke. The use of statins to individuals with atrial fibrillation has been shown to be effective in improving their prognosis. In addition, the drug will aid in the prevention of future ischemic attacks and cardiovascular events). The usage of simvastatin 10mg PO should also be included in the treatment regimen, according to experts. The medicine is beneficial because it contributes to the resolution of the hyperlipidemia problem. In addition, since the patient is using anticoagulants such as the prescription warfarin, HM should avoid administering Motrin to the client (Colussi, et al, 2018). When patients consume the two medicines simultaneously, the odds of experiencing severe bleeding increase significantly. When it comes to the pain that HM is experiencing, the best suitable medicine to use is Tylenol 325mg 2 tabs PO every six-eight hours on the hour. It is very helpful in the treatment of chronic pain Pharmacotherapy for Cardiovascular Disorders Essay Assignment Paper.


Arcangelo, V. P., & Peterson, A. M. (Eds.). (2017). Pharmacotherapeutics for advanced practice: a practical approach (Vol. 536). Lippincott Williams & Wilkins.

Choi, S. Y., Kim, M. H., Lee, K. M., Cho, Y., Park, J. S., Yun, S., & Lip, G. Y. (2020). Age-dependent anticoagulant therapy for atrial fibrillation patients with intermediate risk of ischemic stroke: A nationwide population-based study. Thrombosis and Haemostasis, 121(09), 1151-1160.

Colussi, G., Zuttion, F., Bais, B., Dolso, P., Valente, M., Gigli, G., Gasparini, D., Sponza, M., Catena, C., Sechi, L., & Cavarape, A. (2018). Pre-procedural Statin use is associated with improved long-term survival and reduced major cardiovascular events in patients undergoing carotid artery stenting: A retrospective study. Journal of Clinical Medicine, 7(9), 286.

Korhonen, M. J., Pentti, J., Hartikainen, J., Ilomäki, J., Setoguchi, S., Liew, D., Kivimäki, M., & Vahtera, J. (2020). Lifestyle changes in relation to initiation of antihypertensive and lipid‐lowering medication: A cohort study. Journal of the American Heart Association, 9(4). Pharmacotherapy for Cardiovascular Disorders Essay Assignment Paper

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